Lamin B2 Rabbit pAb

Polyclonal Antibodies

Store at -20°C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy.

Recombinant fusion protein containing a sequence corresponding to amino acids 341-620 of human Lamin B2 (NP_116126.3).

70kDa

Epigenetics Nuclear Signaling, Cell Biology Developmental Biology, Apoptosis, Cytoskeleton, Intermediate Filaments.

84823

LMNB2