Phospho-Cdk1/2-T14 Rabbit mAb

Phosphorylated Antibodies

Store at -20°C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

A synthetic phosphorylated peptide around T14 of human Cdk1/2CDK1 (P06493).

34kDa

Cell Biology Cell Cycle Kinases/Phosphatases CdksNeuroscience Neurology process Neural Signal TransductionNeuroscience Neurology process Neurodegenerative disease OtherEpigenetics and Nuclear Signaling Cell cycle Kinases/Phosphatases CdksCancer Cell cycle Kinases/phosphatases Cdks.

983/1017

CDK1/CDK2