FoxO3a Rabbit pAb

Polyclonal Antibodies

Store at -20°C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Enables DNA binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and mitochondrial transcription factor activity. Involved in several processes, including mitochondrial transcription; positive regulation of muscle atrophy; and positive regulation of pri-miRNA transcription by RNA polymerase II. Acts upstream of or within several processes, including extrinsic apoptotic signaling pathway in absence of ligand; female gonad development; and neuronal stem cell population maintenance. Located in cytosol; mitochondrial outer membrane; and nucleus. Part of protein-containing complex. Colocalizes with mitochondrial matrix. Is expressed in several structures, including alimentary system; brain; early embryo; genitourinary system; and hemolymphoid system. Used to study dermoid cyst of ovary. Orthologous to human FOXO3 (forkhead box O3).

Recombinant fusion protein containing a sequence corresponding to amino acids 558-635 of mouse FOXO3A (NP_062714.1).

71kDa

Epigenetics & Nuclear Signaling, Transcription Factors, Signal Transduction, G protein signaling, G2/M DNA Damage Checkpoint, MAPK-Erk Signaling Pathway, Cell Biology & Developmental Biology, Autophagy, Cell Cycle, G1/S Checkpoint, Endocrine & Metabolism, Insulin Receptor Signaling Pathway, Immunology & Inflammation, B Cell Receptor Signaling Pathway.

2309

Foxo3