Bcl10

Hersteller Abclonal
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse
Applikationen WB, IHC
Protein Familie Lymphocyte Signaling
Menge 100ug
Host Rabbit
ArtNr A0191
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
*

DESCRIPTION

Calculated MW
26kDa
Immunogen
Recombinant protein of human BCL10
Gene ID
8915
Swiss Prot
O95999
Synonyms
CLAP; mE10; CIPER; c-E10; CARMEN;
Isotype
IgG
Purity
Affinity purification
Storage Buffer
Store at -20? or -80?. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.
Recommended Dilutions
WB 1:500-1:2000 IHC 1:50-1:200
illustration
Western blot analysis of extracts of Mouse ovary, using BCL10 antibody.

Arbeitsanleitung

A0191.pdf

Menge: 100ug
Lieferbar: In stock
Listenpreis: 289,30 €
Preis: 289,30 €
lieferbar

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Arne Pelz

sales@hoelzel.de