Smac/Diablo

Hersteller Abclonal
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse, Rat
Applikationen WB, IHC
Protein Familie Apoptosis/Autophagy
Menge 100ug
Host Rabbit
ArtNr A0853
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
*

DESCRIPTION

Calculated MW
27kDa
Immunogen
Recombinant protein of human DIABLO
Gene ID
56616
Swiss Prot
Q9NR28
Synonyms
DIABLO-S; FLJ10537; FLJ25049; SMAC; SMAC3
Isotype
IgG
Purity
Affinity purification
Storage Buffer
Store at -20? or -80?. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Recommended Dilutions
WB 1:500-1:1000 IHC 1:50-1:100
illustration
Western blot analysis of extracts of HepG2 cellslines, using DIABLO antibody.
Menge: 100ug
Lieferbar: In stock
Listenpreis: 289,30 €
Preis: 289,30 €
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