« Back
Home /
Smac/Diablo

Smac/Diablo

Manufacturer	Abclonal
Type	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Applications	WB, IHC
Protein Family	Apoptosis/Autophagy
Amount	100ug
Host	Rabbit
Item no.	A0853
eClass 6.1	32160702
eClass 9.0	32160702
Available
*	DESCRIPTION
Calculated MW	27kDa
Immunogen	Recombinant protein of human DIABLO
Gene ID	56616
Swiss Prot	Q9NR28
Synonyms	DIABLO-S; FLJ10537; FLJ25049; SMAC; SMAC3
Isotype	IgG
Purity	Affinity purification
Storage Buffer	Store at -20? or -80?. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background	This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Recommended Dilutions	WB 1:500-1:1000 IHC 1:50-1:100
illustration	Western blot analysis of extracts of HepG2 cellslines, using DIABLO antibody.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.