ACVRL1 Rabbit pAb

Polyclonal Antibodies

Store at -20°C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH7.3.

This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.

Recombinant fusion protein containing a sequence corresponding to amino acids 234-503 of human ACVRL1 (NP_001070869.1).

56kDa

Cancer, Signal Transduction, Kinase, Cell Biology Developmental Biology, Growth factors, Endocrine Metabolism, Amino acid metabolism, Cardiovascular, Angiogenesis.

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ACVRL1