KLF5 Rabbit pAb

Polyclonal Antibodies

Store at -20°C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.

This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants.

Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human KLF5 (NP_001721.2).

51kDa

Epigenetics Nuclear Signaling, Transcription Factors, Cancer, Tumor suppressors, p53 pathway, Cell Biology Developmental Biology, Apoptosis, Stem Cells, Mesenchymal Stem Cells, Cardiovascular, Angiogenesis, Heart, Hypertrophy.

688

KLF5