STING/TMEM173 Rabbit pAb

ice pack

42kDa

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Recombinant fusion protein containing a sequence corresponding to amino acids 139-379 of human STING/TMEM173 (NP_938023.1).

42kDa

Epigenetics Nuclear Signaling, Cancer, Immunology Inflammation, Cytokines, Cell Intrinsic Innate Immunity Signaling Pathway.

340061

STING1