DNA-Directed RNA Polymerase II Subunit RPB1 (POLR2A) Antibody

DNA-Directed RNA Polymerase II Subunit RPB1 (POLR2A)

POLR2A Antibody is a Rabbit Polyclonal antibody against POLR2A. This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.

POLR2A

Purified by affinity chromatography.

180660