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Mouse PRMT1 isoform2, 1-353 aa, mouse, His-MBP tagged, Recombinant, E.coli

ArtNr ARP-01-2291-100
Hersteller American Research Products
Menge 100 ug
Quantity options 0.5 mg 100 ug 20 ug
Kategorie
Typ Proteins Recombinant
Specific against other
Purity > 90% by SDS - PAGE
Sequence MHHHHHHMKI EEGKLVIWIN GDKGYNGLAE VGKKFEKDTG IKVTVEHPDK LEEKFPQVAA TGDGPDIIFW AHDRFGGYAQ SGLLAEITPD KAFQDKLYPF TWDAVRYNGK LIAYPIAVEA LSLIYNKDLL PNPPKTWEEI PALDKELKAK GKSALMFNLQ EPYFTWPLIA ADGGYAFKYE NGKYDIKDVG VDNAGAKAGL TFLVDLIKNK HMNADTDYSI AEAAFNKGET AM
Citations Herrmann F., et al. (2005). J Biol Chem. 280(45):38005-10.Abramovich C., et al. (1997). EMBO J. 16(2):260-6.
NCBI AAF37293
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Mrmt1, Hrmt112, AW214366, Protein arginine N-methytransferase 1, PRMT1 isoform2, PRMT1, Protein arginine N-methyltransferase 1 ANM 1, HCP 1, HMT1 hnRNP methyltransferase, Heterogeneous nuclear ribonucleoproteins methyltransferase like 2, HMT2, HRMT1 L2, HRMT1L 2, Heterogeneous nuclear ribonucleoproteins methyltransferase like2, HMT 2, HMT1 (hnRNP methyltransferase S, cerevisiae) like 2, HMT1 hnRNP methyltransferase like 2, HMT1 hnRNP methyltransferase like 2 (S, cerevisiae), Human mRNA for suppressor for yeast mutant, Human mRNA for suppressor for yeast mutant complete cds, Interferon receptor 1 bound protein 4, Interferon receptor 1 bound protein4, Interferon receptor 1bound protein 4, IR1 B4, IR1B 4, Mrmt 1, Mrmt1, PRMT 1, R1B4, S, cerevisiae like 2, Protein arginine N methyltransferase 1, Protein arginine N methyltransferase1,
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Description
Protein arginine N-methyltransferase 1(PRMT1) is a type I methyltransferase that transfers a methyl group from S-adenosylmethionine to guanidino nitrogens of arginine residues to form monomethylarginine and asymmetric dimethylarginine. Functions of type I arginine methylation in proteins may include regulation of transcription, modulation of the affinity of nucleic acid-binding proteins, regulation of interferon signaling pathways, and targeting of nuclear proteins. Mouse PRMT1(AAF37293) shares 99.9% sequence identity with the human proteins(NP_938074). Recombinant mouse PRMT1, fused to His-MBP tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Form
Liquid in 40mM Tris pH 8.0, 100mM NaCl, 4mM MgCl2, 2mM DTT, 40% glycerol
Storage
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms
Mrmt1, Hrmt112, AW214366, Protein arginine N-methytransferase 1, PRMT1 isoform2, PRMT1, Protein arginine N-methyltransferase 1 ANM 1, HCP 1, HMT1 hnRNP methyltransferase, Heterogeneous nuclear ribonucleoproteins methyltransferase like 2, HMT2, HRMT1 L2, HRMT1L 2, Heterogeneous nuclear ribonucleoproteins methyltransferase like2, HMT 2, HMT1 (hnRNP methyltransferase S, cerevisiae) like 2, HMT1 hnRNP methyltransferase like 2, HMT1 hnRNP methyltransferase like 2 (S, cerevisiae), Human mRNA for suppressor for yeast mutant, Human mRNA for suppressor for yeast mutant complete cds, Interferon receptor 1 bound protein 4, Interferon receptor 1 bound protein4, Interferon receptor 1bound protein 4, IR1 B4, IR1B 4, Mrmt 1, Mrmt1, PRMT 1, R1B4, S, cerevisiae like 2, Protein arginine N methyltransferase 1, Protein arginine N methyltransferase1,
Concentration
1 mg/ml (determined by Bradford assay)
NCBI
  • AAF37293
References
  • Herrmann F., et al. (2005). J Biol Chem. 280(45):38005-10.
  • Abramovich C., et al. (1997). EMBO J. 16(2):260-6.
Antigen Recognized in Species
Mouse
Purity
>, 90% by SDS - PAGE
Molecular Weight
84 kDa (750 aa)
Amino Acid Sequence
MHHHHHHMKI EEGKLVIWIN GDKGYNGLAE VGKKFEKDTG IKVTVEHPDK LEEKFPQVAA TGDGPDIIFW AHDRFGGYAQ SGLLAEITPD KAFQDKLYPF TWDAVRYNGK LIAYPIAVEA LSLIYNKDLL PNPPKTWEEI PALDKELKAK GKSALMFNLQ EPYFTWPLIA ADGGYAFKYE NGKYDIKDVG VDNAGAKAGL TFLVDLIKNK HMNADTDYSI AEAAFNKGET AMTINGPWAW SNIDTSKVNY GVTVLPTFKG QPSKPFVGVL SAGINAASPN KELAKEFLEN YLLTDEGLEA VNKDKPLGAV ALKSYEEELA KDPRIAATME NAQKGEIMPN IPQMSAFWYA VRTAVINAAS GRQTVDEALK DAQTNSSSNN NNNNNNNNLG IEGRGSHMAA AEAANCIMEV SCGQAESSEK PNAEDMTSKD YYFDSYAHFG IHEEMLKDEV RTLTYRNSMF HNRHLFKDKV VLDVGSGTGI LCMFAAKAGA RKVIGIECSS ISDYAVKIVK ANKLDHVVTI IKGKVEEVEL PVEKVDIIIS EWMGYCLFYE SMLNTVLHAR DKWLAPDGLI FPDRATLYVT AIEDRQYKDY KIHWWENVYG FDMSCIKDVA IKEPLVDVVD PKQLVTNACL IKEVDIYTVK VEDLTFTSPF CLQVKRNDYV HALVAYFNIE FTRCHKRTGF STSPESPYTH WKQTVFYMED YLTVKTGEEI FGTIGMRPNA KNNRDLDFTI DLDFKGQLCE LSCSTDYRMR
Gene Category
Histone Related

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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