CABP7, 1-188aa, Human, His tag, E.coli

CABP7, also known as Calcium-binding protein 7, contains two EF-hand domains. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. The CaBP family of EF-hand containing small Ca (2+)-binding proteins has recently emerged as important regulators of multiple targets essential to normal neuronal function in the mammalian central nervous system. Recombinant human CABP7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

0.5 mg/ml (determined by Bradford assay)

• McCue H.V., et al. (2009) Biochem. Biophys. Res. Commun. 380:825-831
• Yu L. R., et al. (2007) J. Proteome Res. 6:4150-4162

>, 80% by SDS - PAGE

MGSSHHHHHH SSGLVPRGSH MPFHPVTAAL MYRGIYTVPN LLSEQRPVDI PEDELEEIRE AFKVFDRDGN GFISKQELGT AMRSLGYMPN EVELEVIIQR LDMDGDGQVD FEEFVTLLGP KLSTSGIPEK FHGTDFDTVF WKCDMQKLTV DELKRLLYDT FCEHLSMKDI ENIIMTEEES HLGTAEECPV DVETCSNQQI RQTCVRKS