TNFRSF17, 78-184aa, Human, His tag, E.coli

Tumor necrosis factor receptor superfamily member 17, also known as TNFRSF17, is a member of the TNF-receptor superfamily. The open reading frame of the gene encoding TNFRSF17 predicts a 184 amino acid protein with a single transmembrane domain that has no homology with any known protein sequences. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. TNFRSF17 also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. Recombinant human TNFRSF17 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

0.5 mg/ml (determined by Bradford assay)

• Chae S C., et al. (2010) Mol Cells. 29(1): 21-8
• Barone F., et al. (2009) Mucosal Immunol. 2(6): 495-503.

>, 90% by SDS - PAGE

MGSSHHHHHH SSGLVPRGSH MGSRKINSEP LKDEFKNTGS GLLGMANIDL EKSRTGDEII LPRGLEYTVE ECTCEDCIKS KPKVDSDHCF PLPAMEEGAT ILVTTKTNDY CKSLPAALSA TEIEKSISAR