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BPIFA1, 20-256aa, Human, His tag, E.coli

ArtNr ARP-01-P1908-0.5
Hersteller American Research Products
Menge 0.5 mg
Quantity options 0.5 mg 100 ug 20 ug
Kategorie
Typ Proteins Recombinant
Specific against other
Purity > 90% by SDS - PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSQFGGLPV PLDQTLPLNV NPALPLSPTG LAGSLTNALS NGLLSGGLLG ILENLPLLDI LKPGGGTSGG LLGGLLGKVT SVIPGLNNII DIKVTDPQLL ELGLVQSPDG HRLYVTIPLG IKLQVNTPLV GASLLRLAVK LDITAEILAV RDKQERIHLV LGDCTHSPGS LQISLLDGLG PLPIQGLLDS LTGILNKVLP ELVQGNVCPL VN
Citations Ghafouri B., et al. (2004) Biochem Biophys Acta. 1699:57-63.Bingle C D., et al. (2002) Hum Mol Genet. 11: 937-943.
NCBI NP_057667
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias BPI fold-containing family A, member 1, bA49G10.5, LPLUNC3, LUNX, NASG, PLUNC, SPURT
Lieferbar
Description
BPIFA1, also known as PLUNC, belongs to the short subfamily of PLUNC family proteins and have homology only to the Nterminal domains of BPI. It is a secreted protein that is expressed in the secretory ducts and submucosal glands of tracheobronchial tissues. BPIFA1 binds to lipopolysaccharide (LPS) in nasal lavage fluid (NLF) which points to its role in the inflammatory response of the upper airways after exposure to irritants. Decreased levels of BPIFA1 occur in the NLF of smokers and people who have been exposed to reactive epoxy chemicals, indicating that long-term exposure to airway irritants impairs the production of BPIFA1 in the upper respiratory tract. Recombinant human BPIFA1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Form
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 30% glycerol
Storage
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms
BPI fold-containing family A, member 1, bA49G10.5, LPLUNC3, LUNX, NASG, PLUNC, SPURT
Concentration
1 mg/ml (determined by BCA assay)
NCBI
NP_057667
References
  • Ghafouri B., et al. (2004) Biochem Biophys Acta. 1699:57-63.
  • Bingle C D., et al. (2002) Hum Mol Genet. 11: 937-943.
Antigen Recognized in Species
Human
Purity
>, 90% by SDS - PAGE
Molecular Weight
27.1 kDa (260aa), confirmed by MALDI-TOF
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MGSQFGGLPV PLDQTLPLNV NPALPLSPTG LAGSLTNALS NGLLSGGLLG ILENLPLLDI LKPGGGTSGG LLGGLLGKVT SVIPGLNNII DIKVTDPQLL ELGLVQSPDG HRLYVTIPLG IKLQVNTPLV GASLLRLAVK LDITAEILAV RDKQERIHLV LGDCTHSPGS LQISLLDGLG PLPIQGLLDS LTGILNKVLP ELVQGNVCPL VNEVLRGLDI TLVHDIVNML IHGLQFVIKV
Gene Category
Immunology

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Menge: 0.5 mg
Lieferbar: In stock
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