| Description |
Goat anti-Neuroserpin Antibody
Principle Name: Neuroserpin
Official Symbol: SERPINI1
All Name and Symbols: SERPINI1; neuroserpin; PI12; serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1; protease inhibitor 12 (neuroserpin); serpin peptidase inhibitor, clade I (neuroserpin), member 1; DKFZp781N13156
Accession Number(s): NP_005016.1
Peptide Sequence: TMNTSGHDFEEL, is from C Terminus
Human Gene ID(s): 5274
Non-Human GeneID(s):
Important Comments: Reported variants represent identical protein (NP_005016.1; NP_001116224.1).
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As: lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20C. Minimize freezing and thawing.
Applications: Pep ELISA, WB
Tested Species: Human
Peptide ELISA: antibody detection limit dilution 1 to 32000.
Western Blot: Approx 48kDa band observed in Human Brain lysate (calculated MW of 46.4kDa according to NP_005016.1). Recommended concentration: 1-3ug/ml.
Reference(s): Onda M, Belorgey D, Sharp LK, Lomas DA. Latent Ser49Pro neuroserpin forms polymers in the dementia familial encephalopathy with neuroserpin inclusion bodies. J Biol Chem. 2005 Jan 21; [Epub ahead of print] .PMID: 15664988
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