Goat anti-SH2D1A / SAP Antibody

Goat anti-SH2D1A / SAP Antibody
Principle Name: SH2D1A / SAP
Official Symbol: SH2D1A
All Name and Symbols: SH2D1A; SAP; SH2 domain protein 1A, Duncan's disease (lymphoproliferative syndrome); HGNC:10820; DSHP; EBVS; IMD5; LYP; MTCP1; XLP; XLPD ; SH2 domain protein 1A; SLAM (signaling lymphocyte activation molecule) associated protein; RP5-1052M9.3; FLJ18687;
Accession Number(s): NP_002342.1; NP_001108409.1
Peptide Sequence: HKRYFRKIKN, is from internal region
Human Gene ID(s): 4068
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As: lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20C. Minimize freezing and thawing.
Applications: Pep ELISA, WB, IP
Peptide ELISA: antibody detection limit dilution 1 to 16000.
Western Blot: Approx 16kDa band observed in Human Thymus lysates (calculated MW of 14.2xkDa according to NP_002342.1). In transfected HEK293 transiently expressing SH2D1A a band of approx. 16kDa is observed. This band is not observed in the non-transfect
Reference(s): Mikhalap SV, Shlapatska LM, Yurchenko OV, Yurchenko MY, Berdova GG, Nichols KE, Clark EA, Sidorenko SP. The adaptor protein SH2D1A regulates signaling through CD150 (SLAM) in B cells. Blood. 2004 Dec 15; 104(13):4063-70. Epub 2004 Aug 17. .PMID: 15315965