| Description |
Goat anti-SCN5A Antibody
Principle Name: SCN5A
Official Symbol: SCN5A
All Name and Symbols: SCN5A; CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; ICCD; HH1; IVF; LQT3; SSS1; PFHB1; SSS1; sodium channel, voltage-gated, type V, alpha subunit; Nav1.5; sodium channel, voltage-gated, type V, alpha (long QT syndrome 3); cardiac sodium channel alpha subunit; sod
Accession Number(s): NP_932173.1; NP_000326.2; NP_001092874.1; NP_001092875.1; NP_001153632.1; NP_001153633.1
Peptide Sequence: ETDDQSPEKIN, is from internal region
Human Gene ID(s): 6331
Non-Human GeneID(s):
Important Comments: This antibody is expected to recognise all reported isoforms (NP_932173.1; NP_000326.2; NP_001092874.1; NP_001092875.1).
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As: lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20C. Minimize freezing and thawing.
Applications: Pep ELISA
Tested Species:
Peptide ELISA: antibody detection limit dilution 1 to 32000.
Western Blot: Preliminary experiments in lysates of Human Breast and Heart tissues gave no specific signal but low background (at antibody concentration up to 1ug/ml). We would appreciate any feedback from people in the field - have any results been repo
Reference(s): Olson TM, Michels VV, Ballew JD, Reyna SP, Karst ML, Herron KJ, Horton SC, Rodeheffer RJ, Anderson JL. Sodium channel mutations and susceptibility to heart failure and atrial fibrillation. JAMA. 2005 Jan 26; 293(4):447-54. .PMID: 15671429
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