Goat anti-CCKBR Antibody

Pep ELISA, WB, IHC

Goat anti-CCKBR Antibody
Principle Name: CCKBR
Official Symbol: CCKBR
All Name and Symbols: CCKBR; cholecystokinin B receptor ; HGNC:1571; CCK-B; GASR; CCK2 receptor; cholecystokinin-B receptor/gastrin receptor; gastrin receptor; gastrin\cholecystokinin brain receptor; CCK2R
Accession Number(s): NP_795344.1
Peptide Sequence: FDGDSDSDSQSRVRNQ, is from internal region
Human Gene ID(s): 887
Non-Human GeneID(s): 12426 (mouse); 25706 (rat);
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As: lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20C. Minimize freezing and thawing.
Peptide ELISA: antibody detection limit dilution 1 to 16000.
Western Blot: Approx 80kDa band observed in Mouse Pancreas and Rat Stomach lysates (calculated MW of 49.2kDa according to Mouse NP_031653.1and 49.0kDa according to Rat NP_037297.1). The observed molecular weight also corresponds to earlier findings in l
Immunohistochemistry: Paraffin embedded Human Uterus. Recommended concentration: 5ug/ml. In paraffin embedded Human Pancreas expression of CCKBR is detected in islet cells, and not in surrounding acinar cells. Recommended concentration: 6ug/ml.
Reference(s): Olszewska-Pazdrak B, Townsend CM Jr, Hellmich MR. Agonist-independent activation of Src tyrosine kinase by a cholecystokinin-2 (CCK2) receptor splice variant. J Biol Chem. 2004 Sep 24; 279(39):40400-4. Epub 2004 Jul 29. .PMID: 15292208