Goat anti-IL6R / CD126 (isoform 1) Antibody

Goat anti-IL6R / CD126 (isoform 1) Antibody
Principle Name: IL6R / CD126 (isoform 1)
Official Symbol: IL6R
All Name and Symbols: IL6R; interleukin 6 receptor ; HGNC:6019; CD126; IL-6R-1; IL-6R-alpha; IL6RA; MGC104991 ; CD126 antigen; interleukin 6 receptor alpha subunit
Accession Number(s): NP_000556.1
Peptide Sequence: DNTSSHNRPDARD, is from internal region
Human Gene ID(s): 3570
Non-Human GeneID(s):
Important Comments: This antibody is expected to recognise isoform 1 only (NP_000556.1)
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As: lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20C. Minimize freezing and thawing.
Applications: Pep ELISA
Tested Species:
Peptide ELISA: antibody detection limit dilution 1 to 8000.
Western Blot: Preliminary experiments gave an approx 26-28kDa band in Human Bone Marrow and Tonsil lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calcul
Reference(s): Moran DM, Mayes N, Koniaris LG, Cahill PA, McKillop IH. Interleukin-6 inhibits cell proliferation in a rat model of hepatocellular carcinoma. Liver Int. 2005 Apr; 25(2):445-57. .PMID: 15780071