Goat anti-p75NTR / CD271 (aa202-215) Antibody

Pep ELISA, WB

Goat anti-p75NTR / CD271 (aa202-215) Antibody
Principle Name: p75NTR / CD271 (aa202-215)
Official Symbol: NGFR
All Name and Symbols: NGFR; nerve growth factor receptor; CD271; Gp80-LNGFR; TNFRSF16; p75(NTR); p75NTR; NGF receptor; OTTHUMP00000220319; TNFR superfamily, member 16; low affinity nerve growth factor receptor; low affinity neurotrophin receptor p75NTR; low-affinity nerve grow
Accession Number(s): NP_002498.1
Peptide Sequence: PEGSDSTAPSTQEP, is from internal region
Human Gene ID(s): 4804
Non-Human GeneID(s): 18053 (mouse); 24596 (rat);
Important Comments: This antibody is expected to recognize the extracellular domain of p75NTR.
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As: lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20C. Minimize freezing and thawing.
Peptide ELISA: antibody detection limit dilution 1 to 4000.
Western Blot: Approx 75kDa band observed in Rat Heart lysates (calculated MW of 45.2kDa according to Human NP_002498.1 and 45.4kDa according to Rat NP_036742.2. The observed molecular weight corresponds to earlier findings in literature with different an
Reference(s): Colombo E, Romaggi S, Medico E, Menon R, Mora M, Falcone C, Lochmüller H, Confalonieri P, Mantegazza R, Morandi L, Farina C. Human neurotrophin receptor p75NTR defines differentiation-oriented skeletal muscle precursor cells: implications for muscle regeneration. J Neuropathol Exp Neurol. 2011 Feb; 70(2):133-42.PMID: 21343882