Mouse Monoclonal Antibody to Myoglobin

Mouse IgG1

Enterez GeneID: 4151
General Information: Myoglobin (MB), with 154-amino acid protein (about 17kDa), is a member of the globin superfamily and expression of myoglobin is highest in skeletal and cardiac muscle. Functionally, myoglobin is well accepted as an O2-storage protein in muscle, capable of releasing O2 during periods of hypoxia or anoxia. Myoglobin is also thought to buffer intracellular O2 concentration when muscle activity increases and to facilitate intracellular O2 diffusion by providing a parallel path that augments simple diffusion of dissolved O2. Furthermore, myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.
Immunogen: Purified recombinant fragment of Myoglobin expressed in E. Coli.
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Purified antibody in PBS containing 0.03% sodium azide.
Reconstitution and Storage: Reconstituted with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; IHC: 1 to 200 - 1 to 1000
References: 1. Angelique W. Whitehurst, Fred L. Robinson, Mary Shannon Moore. J. Biol. Chem., Mar 2004; 279: 12840 ¿ 12847. ; 2. N Hatano, Y Mori, M Oh-hora. Genes Cells, Nov 2003; 8: 847 - 856. ;