Mouse Monoclonal Antibody to BCL-2

Mouse IgG1

MW: 26kDa
Enterez GeneID: 596
General Information: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.Tissue specificity: Expressed in a variety of tissues.
Immunogen: Synthetic peptide corresponding to residues surrounding BCL-2, conjugated to KLH.
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage: Reconstituted with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; IHC: 1 to 200 - 1 to 1000; ICC: 1 to 200 - 1 to 1000; FCM: 1 to 200 - 1 to 400
References: 1. Cancer Res. 2008 Apr 15; 68(8):2745-54 ; 2. Immunity. 2008 Sep 19; 29(3):391-403. ;