Mouse Monoclonal Antibody to IL3RA

Mouse IgG1

MW: 43.3kDa
Enterez GeneID: 3563
General Information: The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. ; ; ; ;
Immunogen: Purified recombinant fragment of human IL3RA (AA: 200-305) expressed in E. Coli.
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage: Reconstituted with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; ICC: 1 to 200 - 1 to 1000; FCM: 1 to 200 - 1 to 400
References: 1. Biochem Pharmacol. 2012 Aug 1; 84(3):366-73. ; 2. Arch Dermatol Res. 2012 Jan; 304(1):57-63. ;