Mouse Monoclonal Antibody to PPARGC1B

Mouse IgG1

MW: 113.2kDa
Enterez GeneID: 133522
General Information: The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.
Immunogen: Purified recombinant fragment of human PPARGC1B (AA: 195-414) expressed in E. Coli.
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Purified antibody in PBS with 0.05% sodium azide.
Reconstitution and Storage: Reconstituted with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; FCM: 1 to 200 - 1 to 400
References: 1. Free Radic Biol Med. 2012 May 1; 52(9):1692-7.; 2. Neurobiol Dis. 2010 Jan; 37(1):77-85.