Mouse Monoclonal Antibody to CASP-7

Mouse IgG1

MW: 34.3kDa
Enterez GeneID: 840
General Information: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen: Purified recombinant fragment of human CASP-7 (AA: 29-198) expressed in E. Coli.
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Purified antibody in PBS with 0.05% sodium azide.
Reconstitution and Storage: Reconstituted with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; IHC: 1 to 200 - 1 to 1000; FCM: 1 to 200 - 1 to 400
References: 1. Liver Int. 2013 May; 33(5):714-21. doi: 10.1111/liv.12128. Epub 2013 Feb 24. ; 2. Cell Biochem Biophys. 2011 Jun; 60(1-2):113-8.