Mouse Monoclonal Antibody to ATG5

Mouse IgG2b

MW: 32.4kDa
Enterez GeneID: 9474
General Information: The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.
Immunogen: Purified recombinant fragment of human ATG5 (AA: 144-275) expressed in E. Coli.
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage: Reconstituted with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; ICC: N to A; FCM: 1 to 200 - 1 to 400; IHC: N to A
References: 1.PLoS One. 2014 Oct 17; 9(10):e110293.2.Sci Transl Med. 2013 Sep 11; 5(202):202ra123.