Mouse Monoclonal Antibody to Dynamin-2

Mouse IgG2a

MW: 98kDa
Enterez GeneID: 1785
General Information: Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.
Immunogen: Purified recombinant fragment of human Dynamin-2 (AA: 520-744) expressed in E. Coli.
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage: Reconstituted with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; ICC: N to A; FCM: N to A; IHC: N to A
References: 1.Cancer Med. 2014 Feb; 3(1):14-24.2.Eur J Obstet Gynecol Reprod Biol. 2012 Oct; 164(2):180-4.