Fibroblast Growth Factor Receptor 4 Fc Chimera Human Recombinant

Lyophilized powder at room temperature.

Soluble FGFR-4a (IIIc) Fc Chimera Human Recombinant fused with Xa cleavage site with the Fc part of human IgG1 produced in baculovirus is a heterodimeric, glycosylated, Polypeptide chain and having a molecular mass of 170 kDa. The FGFR4 is purified by proprietary chromatographic techniques.
Source: Insect Cells.
Physical Appearance and Stability: Lyophilized FGFR4 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution FGFR4 should be stored at 4C between 2-7 days and for future use below -18C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Formulation and Purity: CD334 was lyophilized from a concentrated (1mg/ml) sterile solution containing no additives. Greater than 90.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Solubility: It is recommended to reconstitute the lyophilized FGFR-4 in sterile PBS not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity: Determined by its ability to inhibit human FGF acidic-dependent proliferation on R1 cells. The ED50 for this effect is typically at 15.0-30.0 ng/ml.