Description |
Product Name: Tyrosine Kinase ErbB-3 Human Recombinant Synonyms: Receptor tyrosine-protein kinase erbB-3, EC 2.7.10.1, c-erbB3, Tyrosine kinase-type cell surface receptor HER3, ErbB3, HER3. Description: Tyrosine Kinase ErbB3 Human Recombinant (HER3) produced in E.Coli is a single, non-glycosylated polypeptide consisting of several epitopes of extracellular domain of human Erb-b3, and having a total molecular mass of approximately 12.0 kDa.The ErbB3 is purified by proprietary chromatographic techniques. Uniprot Accesion Number: P21860 Amino Acid Sequence: Source: Escherichia Coli. Physical Appearance and Stability: ErbB3 although stable at 4C for 1 week, should be stored below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. Formulation and Purity: Each mg protein contains 1 mg aluminum hydroxide 10mM arginine, 10mM sodium chloride, 20mM sodium phosphate buffer and 5mM potassium phosphate. Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. Application: Solubility: It is recommended that sterile phosphate-buffered saline containing 1mg aluminum hydroxide be added to the vial to prepare a stock solution. Biological Activity: Measured by its ability to postpone tumor emerge time of spontaneous breast cancer in FVB/N transgenic mice and inhibit the development of tumor, effectively inhibit the growth of in situ transplanted breast cancer in FVB/N transgenic mice. Shipping Format and Condition: Lyophilized powder at room temperature. Usage Statement: Our products are furnished forLABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |