Vergleich

Research Grade Etokimab

ArtNr ANSY-DHB74001-1mg
Hersteller AntibodySystem
CAS-Nr. 2022981-44-6
Menge 1 mg
Quantity options 100 ug 1 mg
Kategorie
Typ Biosimilars
Format Liquid
Clon Etokimab
Specific against Human (Homo sapiens)
Isotype IgG1 Kappa
Purity >95% as determined by SDS-PAGE.
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias ANB020,CAS: 2022981-44-6,IL33
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary
Manufacturer - Applications
Research Grade Biosimilar
Manufacturer - Targets
NF-HEV, IL-1F11, C9orf26, IL-33, Interleukin-1 family member 11, IL33, Nuclear factor from high endothelial venules, NFHEV, Interleukin-33, IL1F11
Manufacturer - Host
Humanized
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Product description
ANB020, now called etokimab, is currently in phase 2a testing in eczema, which is also known as atopic dermatitis. Scientists from the Medical Research Council Human Immunology Unit at the University of Oxford released data from 12 patients showing that 83% who were treated with etokimab reported a reduction in disease severity after 29 days. Etokimab, an anti-IL-33 biologic, has previously demonstrated a good safety profile and favorable pharmacodynamic properties in many clinical studies. Etokimab is designed to block interleukin-33 (IL-33), an immune-signaling molecule. In peanut allergy, the body overreacts to peanuts as IL-33 activates an antibody called immunoglobin E. These antibodies cause allergic response such as mouth itchiness, hives, breathing difficulties and potentially fatal anaphylactic shock.
Storage buffer
0.01M PBS, pH 7.4.
Purification
Protein A/G purified from cell culture supernatant.
Note
For research use only. Not suitable for clinical or therapeutic use.
Clonality
Monoclonal
Concentration
1 mg/ml
Recombinant
Yes
Expression System
Mammalian Cells

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 mg
Lieferbar: In stock
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