Vergleich

Research Grade Sotigalimab

ArtNr ANSY-DHD68911-100ug
Hersteller AntibodySystem
CAS-Nr. 2305607-45-6
Menge 100 ug
Quantity options 100 ug 1 mg
Kategorie
Typ Biosimilars
Format Liquid
Clon Sotigalimab
Specific against Human (Homo sapiens)
Isotype IgG1 Kappa
Purity >95% as determined by SDS-PAGE.
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias APX005M,APX-005,APX-005-M,APX-005M,CAS: 2305607-45-6
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary
Manufacturer - Applications
Research Grade Biosimilar
Manufacturer - Category
Biosimilar
Manufacturer - Targets
Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, TNFRSF5, CDw40, CD40
Manufacturer - Host
Humanized
Shipping Temperature
Blue-ice bags
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Product description
The FDA has granted an orphan drug designation to sotigalimab (APX005M) as a potential therapeutic option for patients with soft tissue sarcoma, according to announcement from Apexigen Inc., the drug developer.
A novel, humanized monoclonal antibody, sotigalimab was designed stimulate antitumor immune response and to target CD40, which is a key co-stimulatory receptor that serves to activate innate and adaptive immune systems. When sotigalimab binds to CD40 on antigen-presenting cells, it induces a multifaceted immune response that brings several components of the immune system together to attack the cancer.
Manufacturer - Formula
0.01M PBS, pH 7.4.
Storage buffer
0.01M PBS, pH 7.4.
Purification
Protein A/G purified from cell culture supernatant.
Note
For research use only. Not suitable for clinical or therapeutic use.
Clonality
Monoclonal
Concentration
1 mg/ml
Recombinant
Yes
Expression System
Mammalian Cells

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
lieferbar

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