RSPO3 Antibody

ArtNr	CSB-PA887154LA01HU-50ug
Hersteller	Cusabio
Menge	50 ug
Quantity options	100 ug 20 ug 50 ug
Kategorie	Oncology Neuroscience Metabolism Diabetes Molecular Targets for Neuroscience Antibodies By Cell Type Immunohistochemistry ELISA Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CRISTIN1 antibody,hPWTSR antibody,hRspo3 antibody,Protein with TSP type-1 repeat antibody,PWTSR antibody,R-spondin 3 homolog antibody,R-spondin-3 [Precursor] antibody,R-spondin-3 antibody,Roof plate specific spondin-3 antibody,Roof plate-specific spondin-3 antibody,RSPO3 antibody,RSPO3_HUMAN antibody,Thrombospondin type I domain containing 2 antibody,Thrombospondin type-1 domain-containing protein 2 antibody,THSD2 antibody
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Manufacturer - Targets	RSPO3
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	CRISTIN1 antibody, hPWTSR antibody, hRspo3 antibody, Protein with TSP type-1 repeat antibody, PWTSR antibody, R-spondin 3 homolog antibody, R-spondin-3 [Precursor] antibody, R-spondin-3 antibody, Roof plate specific spondin-3 antibody, Roof plate-specific spondin-3 antibody, RSPO3 antibody, RSPO3_HUMAN antibody, Thrombospondin type I domain containing 2 antibody, Thrombospondin type-1 domain-containing protein 2 antibody, THSD2 antibody
Immunogen Species	Human
Immunogen	Recombinant Human R-spondin-3 protein (22-272AA)
Dilution	ELISA:1:2000-1:10000 IHC:1:20-1:200
Background	Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Stem Cells
Initial Research Areas	Stem Cells
Antigen Species	Human
Antigen	Recombinant Human R-spondin-3 protein (22-272AA)
Clonality	Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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CSB-PA887154LA01HU-50ug-datasheet.pdf

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Menge: 50 ug

lieferbar

Lieferung vsl. bis 18.12.2025