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Rat IgG2a (1-1) In Vivo Isotype Control Low Endotoxin Europäischer Partner

ArtNr ICH2244-1g
Hersteller IchorBio
Menge 1 g
Quantity options 100 mg 1 mg 1 g 25 mg 500 mg 50 mg 5 mg
Kategorie
Typ Antibody Monoclonal
Format Liquid
Clon 1-1
Specific against other
Host Rat
Purity >95% by SDS-PAGE and HPLC
Citations Chuah, S. et al. Uncoupling immune trajectories of response and adverse events from anti-PD-1 immunotherapy in hepatocellular carcinoma. Journal of Hepatology. Volume 77, Issue 3, 2022, Pages 683-694,
Benguigui et al. Interferon-stimulated neutrophils as a predictor of immunotherapy response. 2024, Cancer Cell 42, 253–265
Roichman et al. Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models. Cancer Res 2025
Braun, Lukas M. et al. Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity Cancer Cell, Volume 43, Issue 2, 269 - 291.e19
Patel, A. et al. Targeting Neuronal Nitric Oxide Synthase (nNOS) as a Novel Approach to Enhancing the Anti-Melanoma Activity of Immune Checkpoint Inhibitors. Pharmaceutics 2025, 17, 691.
Liang B. et al. Antagonistic roles of cGAS/STING signaling in colorectal cancer chemotherapy. Front Oncol. 2024 Oct 14;14:1441935.
Liang B. et al. SIX4 Controls Anti-PD-1 Efficacy by Regulating STING Expression. Cancer Research Communications (2023) 3 (11): 2412–2419.
PD-1 Blockade Restores the Proliferation of Peripheral Blood Lymphocyte and Inhibits Lymphocyte Apoptosis in a BALB/c Mouse Model of CP BVDV Acute Infection
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Category
Isotype Controls, monoclonal antibody, IgG2a, Cited
Manufacturer - Targets
KLH
Shipping Temperature
Blue ice
Storage Conditions
This Low Endotoxin Functional Formulation is stable when stored at 2-8°C. Do not freeze.
Aggregation
Aggregation level ≤ 5%
Formulation
This Low Endotoxin Functional Formulation antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Application Notes
This isotype control antibody should be used at the same concentration as the primary antibody.
Concentration
1.0 - 5.0 mg/ml
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity
This Rat IgG2a isotype control (anti-Trinitrophenol + KLH) antibody has been tested against selected species' cells and tissues to assure minimal cross reactivity.
Purification method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Buffer

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 g
Lieferbar: In stock
lieferbar

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