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Anti-Kv7.2/KCNQ2 K+ channel Antibody

ArtNr 73-079
Hersteller Antibodies Incorporated
Menge 5 mL
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IHC, ICC
Clon N26A/23
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Potassium voltage-gated channel subfamily KQT member 2 (KQT-like 2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (Voltage-gated potassium channel subunit Kv7.2)
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibody
Manufacturer - Category
Membrane Channels
Manufacturer - Targets
Kv7.2/KCNQ2 K+ channel
Country of Origin
United States
Shipping Temperature
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight
95 kDa
Manufacturer - Research Area
Rod Cell Markers, Ca2+ Channels, Transporter Proteins
Expiration
24 months from date of receipt
Immunogen
Fusion protein amino acids 1-59 (cytoplasmic N-terminus) of human KCNQ2 (accession number O43526) produced recombinantly in E. Coli
Immunogen Species
Human
Description
Fusion protein amino acids 1-59 (cytoplasmic N-terminus) of human KCNQ2
(also known as Potassium voltage-gated channel subfamily KQT member 2 or KvLQT2, Kv7.2 and KQT-like 2, accession number O43526)
Rat: 96% identity (56/58 amino acids identical)
Mouse: 96% identity (56/58 amino acids identical)
Expected Banding Pattern
95 kDa
Validation
T|Br-IHC
Target Description
Potassium voltage-gated channel subfamily Q member 2 is encoded by the gene KCNQ2. KCNQ2 is a member of the potassium channel family, KQT (TC 1.A.1.15) subfamily, Kv7.2/KCNQ2 sub-subfamily. KCNQ2 associates with KCNQ3 to form a potassium channel with nearly identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness of synaptic inputs. KCNQ2 is expressed in the brain and spinal cord. Diseases associated with KCNQ2 include Epileptic Encephalopathy, Early Infantile, 7 and Seizures, Benign Familial Neonatal 1.
Clonality
Monoclonal
Manufacturer - Specificity
No cross-reactivity reported
Concentration
Lot dependent
Form
TC Supernatant
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.9
Production Notes
Supernatant is harvested from hybridoma cells grown under standard cell culture conditions
Quality Control
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Quality Control: Application
ICC
Dilution Range: WB
1:1000
Usage Statement
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement
We produce our Kv7.2/KCNQ2 K+ channel mouse monoclonal primary antibody from hybridoma clone N26A/23. It is great in IHC, ICC, WB and is TC supernatant.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 5 mL
Lieferbar: In stock
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