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Anti-Kv7.2/KCNQ2 K+ channel Antibody

Anti-Kv7.2/KCNQ2 K+ channel Antibody

Item no.	73-079
Manufacturer	Antibodies Incorporated
Amount	5 mL
Category	Antibodies Primary Antibodies Immunoblot
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IHC, ICC
Clone	N26A/23
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Potassium voltage-gated channel subfamily KQT member 2 (KQT-like 2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (Voltage-gated potassium channel subunit Kv7.2)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibody
Manufacturer - Category	Membrane Channels
Manufacturer - Targets	Kv7.2/KCNQ2 K+ channel
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	95 kDa
Manufacturer - Research Area	Rod Cell Markers, Ca2+ Channels, Transporter Proteins
Expiration	24 months from date of receipt
Immunogen	Fusion protein amino acids 1-59 (cytoplasmic N-terminus) of human KCNQ2 (accession number O43526) produced recombinantly in E. Coli
Immunogen Species	Human
Description	Fusion protein amino acids 1-59 (cytoplasmic N-terminus) of human KCNQ2 (also known as Potassium voltage-gated channel subfamily KQT member 2 or KvLQT2, Kv7.2 and KQT-like 2, accession number O43526) Rat: 96% identity (56/58 amino acids identical) Mouse: 96% identity (56/58 amino acids identical)
Expected Banding Pattern	95 kDa
Validation	T\|Br-IHC
Target Description	Potassium voltage-gated channel subfamily Q member 2 is encoded by the gene KCNQ2. KCNQ2 is a member of the potassium channel family, KQT (TC 1.A.1.15) subfamily, Kv7.2/KCNQ2 sub-subfamily. KCNQ2 associates with KCNQ3 to form a potassium channel with nearly identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness of synaptic inputs. KCNQ2 is expressed in the brain and spinal cord. Diseases associated with KCNQ2 include Epileptic Encephalopathy, Early Infantile, 7 and Seizures, Benign Familial Neonatal 1.
Clonality	Monoclonal
Manufacturer - Specificity	No cross-reactivity reported
Concentration	Lot dependent
Form	TC Supernatant
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.9
Production Notes	Supernatant is harvested from hybridoma cells grown under standard cell culture conditions
Quality Control	Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Quality Control: Application	ICC
Dilution Range: WB	1:1000
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our Kv7.2/KCNQ2 K+ channel mouse monoclonal primary antibody from hybridoma clone N26A/23. It is great in IHC, ICC, WB and is TC supernatant.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 mL

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Delivery expected until 9/11/2025

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