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Anti-BKbeta3a K+ Channel Antibody

ArtNr 75-098
Hersteller Antibodies Incorporated
Menge 100 uL
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IP, IHC, ICC
Clon N40B/18
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Potassium large conductance calcium-activated channel, subfamily M, beta member 3
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibody
Manufacturer - Targets
BKbeta3a K+ channel
Country of Origin
United States
Shipping Temperature
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight
32 kDa
Manufacturer - Research Area
Ion Channels and Modulators, K+ Channels
Expiration
24 months from date of receipt
Immunogen
Fusion protein amino acids 1-49 (unique N-terminus) of mouse BKBeta3a (accession number Q08460) produced recombinantly in E. Coli
Immunogen Species
Mouse
Description
Our Anti-BKbeta3a K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N40B/18. It detects human, mouse, and rat BKbeta3a K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.
Target Description
Calcium-activated potassium channel subunit beta-3, Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 3 or BKBeta3a is encoded by the gene KCNMB3. BKbeta3a can bind to KCNMA1 to form a channel in the calcium activated large conductance (MaxiK channel) family. BKbeta3a acts to modulate the calcium sensitivity and gating kinetics of KCNMA1. It is widely expressed in tissues, and is present in several isoforms. Diseases associated with this gene include Familial Febrile Seizures.
Clonality
Monoclonal
Manufacturer - Specificity
No cross-reactivity against BKBeta1, BKBeta2, BKBeta3b or BKBeta4
Concentration
1 mg/mL
Form
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.25
Production Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Quality Control: Application
ICC
Usage Statement
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement
We produce our BKbeta3a K+ channel mouse monoclonal primary antibody from hybridoma clone N40B/18. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 uL
Lieferbar: In stock
lieferbar

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