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Anti-TRPML3/Mucolipin-3 Antibody

ArtNr 75-283
Hersteller Antibodies Incorporated
Menge 100 uL
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, ICC
Clon N268/19
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG2a
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Mucolipin-3 (Transient receptor potential channel mucolipin 3) (TRPML3)
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibody
Manufacturer - Targets
TRPML3/Mucolipin-3
Country of Origin
United States
Shipping Temperature
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight
64 kDa
Manufacturer - Research Area
Ion Channels and Modulators, Trp Channels
Expiration
24 months from date of receipt
Immunogen
Synthetic peptide amino acids 269-285 (CKDWHVSGSIQKNTHYM, extracellular N-terminus) of human TRPML3 (accession number Q8TDD5)
Immunogen Species
Human
Description
Our Anti-TRPML3/Mucolipin-3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N268/19. It detects human, mouse, and rat TRPML3/Mucolipin-3, and is purified by Protein A chromatography. It is great for use in ICC, WB.
Target Description
Mucolipin-3, Transient receptor potential cation channel, mucolipin subfamily, member 3 or TrpML3 is encoded by the gene MCOLN3. It is a member of the small family of the TRPML channels, a subgroup of the large protein family of TRP ion channels and acts as an inwardly rectifying cation channel. TrpML3 is found in the cochlea, olfactory kidney, lung and hair cells and strial cells of the inner ear. The protein localizes to the plasma membrane, endosomes, and lysosomes of cells. Mutations in this gene in mice result in auditory hair cell death and deafness
Clonality
Monoclonal
Manufacturer - Specificity
No cross-reactivity reported
Concentration
1 mg/mL
Form
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Quality Control: Application
ICC
Usage Statement
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement
We produce our TRPML3/Mucolipin-3 mouse monoclonal primary antibody from hybridoma clone N268/19. It is great in ICC, WB and is purified by Protein A chromatography.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 uL
Lieferbar: In stock
lieferbar

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