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Anti-Cavß3 Calcium Channel Antibody

ArtNr 75-472
Hersteller Antibodies Incorporated
Menge 100 uL
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, ICC
Clon N473/36
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG2b
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3)
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibody
Manufacturer - Targets
Cavß3 calcium channel
Country of Origin
United States
Shipping Temperature
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight
60 kDa
Manufacturer - Research Area
Ion Channels and Modulators, Ca2+ Channels
Expiration
24 months from date of receipt
Immunogen
Fusion protein amino acids 20-149 (N-terminus) of human Cavbeta3 (accession number P54284)
Immunogen Species
Human
Description
Our Anti-Cavß3 calcium channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N473/36. It detects human, mouse, and rat Cavß3 calcium channel, and is purified by Protein A chromatography. It is great for use in ICC, WB.
Target Description
Voltage-dependent L-type calcium channel subunit beta-3 or Cav ß3 is encoded by the gene CACNB3. Cavß3 is a cytoplasmic subunit of voltage-sensitive calcium channels.These channels facilitate entry of calcium ions into excitable cells are involved in a variety of calcium dependent processes, including neurotransmitter release, muscle contraction, and gene expression. Cav ß3 is expressed in brain, colon and ovary. Diseases associated with this gene include Lambert-Eaton Myasthenic Syndrome.
Clonality
Monoclonal
Manufacturer - Specificity
Does not cross-react with Cavbeta1, Cavbeta2 or Cavbeta4
Concentration
1 mg/mL
Form
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
Quality Control: Application
WB Brain
Usage Statement
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement
We produce our Cavß3 calcium channel mouse monoclonal primary antibody from hybridoma clone N473/36. It is great in ICC, WB and is purified by Protein A chromatography.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 uL
Lieferbar: In stock
lieferbar

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