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Puma BH3 Domain Antibody [APR07168G]

Puma BH3 Domain Antibody [APR07168G]

ArtNr	LBI-APR07168G
Hersteller	Leading Biology
Menge	100 ul
Quantity options	100 ul
Kategorie	Antibodies Cell Biology Cell Status Apoptosis Flow Cytometry Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies
Typ	Antibody
Format	Liquid
Applikationen	WB, FC, IF, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Bcl-2-binding component 3, JFY-1, p53 up-regulated modulator of apoptosis, BBC3, PUMA
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Manufacturer - Type	Polyclonal Antibodies
Manufacturer - Category	Abs-G
Storage Conditions	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight	20532
Overview	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality Puma BH3 Domain Antibody [APR07168G].
Manufacturer - Specificity	This Puma BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-154 amino acids from human Puma BH3 Domain.
Cellular localization	Mitochondrion Note=Localized to the mitochondria in order to induce cytochrome c release
Gene Name	BBC3
Function	Essential mediator of p53/TP53-dependent and p53/TP53- independent apoptosis (PubMed:11463391). Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis (PubMed:23340338).
Summary	Tissue Location: Ubiquitously expressed.
Manufacturer - Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB-1:1000IHC-P-1:100~500IF-1:10~50FC-1:10~50
Clonality	Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ul

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Lieferung vsl. bis 16.10.2025

Express-Lieferung: 7 Tage sparen

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