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DLG2 Antibody (Center) [APR11740G]

DLG2 Antibody (Center) [APR11740G]

ArtNr	LBI-APR11740G
Hersteller	Leading Biology
Menge	100 ul
Quantity options	100 ul
Kategorie	Neuroscience Molecular Targets for Neuroscience Neural Signaling Antibodies Western Blot ELISA Primary Antibodies
Typ	Antibody
Applikationen	WB
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Disks large homolog 2, Channel-associated protein of synapse-110, Chapsyn-110, Postsynaptic density protein PSD-93, DLG2
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Manufacturer - Type	Polyclonal Antibodies
Manufacturer - Category	Abs-G
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight	97552
Overview	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality DLG2 Antibody (Center) [APR11740G].
Manufacturer - Specificity	This DLG2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 614-648 amino acids from the Central region of human DLG2.
Cellular localization	Cell membrane {ECO:0000250\|UniProtKB:Q63622}; Lipid-anchor {ECO:0000250\|UniProtKB:Q63622}. Cell junction, synapse, postsynaptic density {ECO:0000250\|UniProtKB:Q63622}. Cell junction, synapse. Membrane {ECO:0000250\|UniProtKB:Q63622}. Cell projection, axon {ECO:0000250\|UniProtKB:Q63622}. Perikaryon {ECO:0000250\|UniProtKB:Q63622}. Note=Concentrated in soma and postsynaptic density of a subset of neurons {ECO:0000250\|UniProtKB:Q63622}
Gene Name	DLG2
Function	Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity).
Dilution	WB-1:1000
Clonality	Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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