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ARHGAP18 Antibody (Center) [APR15009G]

ArtNr LBI-APR15009G
Hersteller Leading Biology
Menge 100 ul
Quantity options 100 ul
Kategorie
Typ Antibody
Format Liquid
Applikationen WB, FC, IHC-P
Specific against Human (Homo sapiens)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Rho GTPase-activating protein 18, MacGAP, Rho-type GTPase-activating protein 18, ARHGAP18 (<a href="http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=21035" target="_blank">HGNC:21035</a>)
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Manufacturer - Type
Polyclonal Antibodies
Manufacturer - Category
Abs-G
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
74977
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality ARHGAP18 Antibody (Center) [APR15009G].
Manufacturer - Specificity
This ARHGAP18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-207 amino acids from the Central region of human ARHGAP18.
Cellular localization
Cytoplasm.
Gene Name
ARHGAP18
Function
Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state (PubMed:21865595). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1 (PubMed:25778702). Regulates cell shape, spreading, and migration (PubMed:21865595).
Manufacturer - Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
WB-1:1000IHC-P-1:100~500FC-1:10~50
Clonality
Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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