Anti-KDEL [Clone 10C3] - 50 µg

Antibody Products>Neuroscience and Signal Transduction Antibodies|Products

Next Day 2 - 8°C

The tetrapeptide KDEL, located at the carboxy-terminal sequences of luminal proteins, is a retrieval motif essential for the precise sorting of these proteins along the secretory pathway. KDEL proteins perform essential functions in the endoplasmic reticulum (ER) related to protein folding as well as assembly. The localization of chaperones and other soluble proteins to the ER is achieved by their continuous retrieval from post-ER compartments by the KDEL receptor which is a membrane protein localized in the Golgi apparatus.

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