Anti-CD31 (Mouse) LIMAAbody® Atto-488

Primary

4-8°C

CD31, also known as PECAM-1, is an adhesion molecule and is expressed on endothelial cells at intercellular junctions and various T cell subsets. It shows altered expression levels in arterial, venous and lymphatic vessels. It is also found to a lesser extent on platelets, as well as most other leukocytes including monocytes and neutrophils. CD31 facilitates homotypic binding to itself, as well as heterotypic binding to the leukocyte integrin alpha V beta III. CD31 plays a crucial role in facilitating the transendothelial migration of leukocytes through the intercellular junctions of vascular endothelial cells. It is one of key regulatory molecules in vascular system.