PPP1R16B Antibody

ArtNr	OACA05624-100UG
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Oncology Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Adenocarcinoma Mesothelioma Immunohistochemistry Western Blot ELISA Autophagy Senescence Cardiovascular Research Proliferation Myocardial Infarction Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Purity	>95%
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ANKRD4;ankyrin repeat domain protein 4;ankyrin repeat domain-containing protein 4;CAAX box protein TIMAP;hTIMAP;protein phosphatase 1 regulatory inhibitor subunit 16B;protein phosphatase 1,regulatory (inhibitor) subunit 16B;TGF-beta-inhibited membrane-associated protein;TIMAP.
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Gene symbol	PPP1R16B
Gene Fullname	protein phosphatase 1 regulatory subunit 16B
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function (PubMed:18586956). Involved in the regulation of the PI3K/AKT signaling pathway, angiogenesis and endothelial cell proliferation (PubMed:25007873). Regulates angiogenesis and endothelial cell proliferation through the control of ECE1 dephosphorylation, trafficking and activity (By similarity). Protects the endothelial barrier from lipopolysaccharide (LPS)-induced vascular leakage (By similarity). Involved in the regulation of endothelial cell filopodia extension (By similarity). May be a downstream target for TGF-beta1 signaling cascade in endothelial cells (PubMed:16263087, PubMed:18586956). Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation (PubMed:18586956). Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1 (PubMed:16263087). Involved in the dephosphorylation of EEF1A1 (PubMed:26497934).
Nucleotide accession_num	NM_001172735
Protein accession_num	NP_001166206
Protein name	Protein phosphatase 1 regulatory inhibitor subunit 16B
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Protein phosphatase 1 regulatory inhibitor subunit 16B protein (101-400AA)

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OACA05624-100UG-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 25.12.2025

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