FES Antibody

ArtNr	OACD03475-1ML
Hersteller	AVIVA Systems Biology
Menge	1 ml
Kategorie	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Neural Transcription Factors Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Adenocarcinoma Immunohistochemistry Immunoprecipitation Western Blot Immunocytochemistry Primary Antibodies Microglia Markers Immunochemistry
Format	Liquid
Applikationen	WB, IP, IHC, ICC
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Alias	feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog;feline sarcoma oncogene;feline sarcoma/Fujinami avian sarcoma oncogene homolog;FPS;Oncogene FES,feline sarcoma virus;p93c-fes;proto-oncogene c-Fes;proto-oncogene c-Fps;proto-oncogene tyrosine-protein kinase Fes/Fps;tyrosine-protein kinase Fes/Fps.
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Molecular Weight	79 kDa
Application Data	Western blotting: 1:50-400 Immunocytochemistry in formalin fixed cells: 1:50-500 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Immunohistochemistry in paraffin section: 1:10-100 Enzyme-linked Immunosorbent Assay: 1:100-1:5, 000 Optimal working dilutions must be determined by end user.
Gene symbol	FES
Gene Fullname	FES proto-oncogene, tyrosine kinase
Product format	Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution and storage	2°C to 8°C\|-20°C
Description of target	Tyrosine-protein kinase that acts downstream of cell surface receptors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, cell attachment and cell spreading. Plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Acts down-stream of the activated FCER1 receptor and the mast/stem cell growth factor receptor KIT. Plays a role in the regulation of mast cell degranulation. Plays a role in the regulation of cell differentiation and promotes neurite outgrowth in response to NGF signaling. Plays a role in cell scattering and cell migration in response to HGF-induced activation of EZR. Phosphorylates BCR and down-regulates BCR kinase activity. Phosphorylates HCLS1/HS1, PECAM1, STAT3 and TRIM28.
Nucleotide accession_num	NM_001143783
Protein accession_num	NP_001137255.1
Protein name	Tyrosine-protein kinase Fes/Fps
Clonality	Polyclonal
Purification	Affinity Purified; Protein A Purified
Immunogen	Range: Leu509 - Asn766
Manufacturer - Specificity	The antibody is a rabbit polyclonal antibody raised against FES. It has been selected for its ability to recognize FES in immunohistochemical staining and western blotting.
Concentration	0.5 mg/ml

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Lieferung vsl. bis 11.12.2025

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