ROS1 Antibody

ArtNr	OACD07054-1ML
Hersteller	AVIVA Systems Biology
Menge	1 ml
Kategorie	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Neural Transcription Factors Molecular Targets for Neuroscience Aging & Neurological Disorders Neural Signaling Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Adenocarcinoma Immunohistochemistry Western Blot ELISA Immunocytochemistry Autophagy Endocrine Regulation of Lipid Metabolism Enzymes Other Fatty Acid Enzymes Primary Antibodies Immunostaining Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC, ICC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	c-ros oncogene 1 ,receptor tyrosine kinase;c-Ros receptor tyrosine kinase;c-ros-1;MCF3;Proto-oncogene c-Ros;proto-oncogene c-Ros-1;proto-oncogene tyrosine-protein kinase ROS;Receptor tyrosine kinase c-ros oncogene 1;ROS;ROS proto-oncogene 1 ,receptor tyrosine kinase;transmembrane tyrosine-specific protein kinase;v-ros avian UR2 sarcoma virus oncogene homolog 1.
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunocytochemistry\|Immunohistochemistry\|Immunohistochemistry-Frozen\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Molecular Weight	264 kDa
Application Data	Western blotting: 1:50-400 Immunocytochemistry in formalin fixed cells: 1:50-500 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Immunohistochemistry in paraffin section: 1:10-100 Enzyme-linked Immunosorbent Assay: 1:100-1:5, 000 Optimal working dilutions must be determined by end user.
Gene symbol	ROS1
Gene Fullname	ROS proto-oncogene 1, receptor tyrosine kinase
Product format	Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution and storage	2°C to 8°C\|-20°C
Description of target	Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.
Nucleotide accession_num	NM_002944
Protein accession_num	NP_002935.2
Protein name	Proto-oncogene tyrosine-protein kinase ROS
Clonality	Polyclonal
Purification	Affinity Purified; Protein A Purified
Immunogen	Range: Leu1945 - Phe2222
Manufacturer - Specificity	The antibody is a rabbit polyclonal antibody raised against ROS1. It has been selected for its ability to recognize ROS1 in immunohistochemical staining and western blotting.
Concentration	1 mg/ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 1 ml

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Lieferung vsl. bis 11.12.2025

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