c-FOS (Cellular oncogene fos)

Antibodies / Antibodies-Transcription Factors

-20°C

Supplied as a liquid in 20mM Tris-HCl, 10mg/ml BSA, pH 8.0, 0.05% sodium azide.

Peptide corresponding to the C-Terminus of human c-FOS.

Cellular oncogene fos (c-Fos) is one of four Fos family proteins that associate with Jun family proteins to form the AP-1 transcription factor complex. It is thought to have an important role in signal transduction, cell proliferation and differentiation. Cellular oncogene fos (c-Fos) is constitutively sumoylated by SUMO1, SUMO2 and SUMO3. Within aa1-132, human c-Fos shares 92% aa sequence identity with mouse and rat c-Fos.

Applications:
Suitable for use in ELISA, Western Blot, Immunoprecipitation, and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:20000-1:50000
Western Blot: 1:2000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.