hnRNP H (Heterogeneous Nuclear Ribonucleoprotein H2, hnRNP H2, FTP-3, Heterogeneous Nuclear Ribonucleoprotein H', hnRNP H', HNRNPH2, FTP3, HNRPH2)

Antibodies / Antibodies-Nuclear Proteins

-20°C

Supplied as a liquid PBS, 15mM sodium azide, pH 7.2.

Synthetic peptide corresponding to amino acids 180-230 of Human hnRNP H.

Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to pre-mRNA processing and transport, and also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. The majority of hnRNP proteins components are localized to the nucleus; however some shuttle between the nucleus and the cytoplasm. Most hnRNP proteins, including hnRNP C1 and C2, contain one or more RNA binding domains and are implicated in the processing of pre-mRNA. hnRNPs F and H are largely related factors that preferentially associate with poly(rG) regions on RNA.

Applications:
Suitable for use in Western Blot, Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Western Blot: 1:500-1:1000
Immunohistochemistry: 1:50-1:200
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.