LTA4H (Leukotriene A(4) Hydrolase, Leukotriene A-4 Hydrolase, Leukotriene A4 Hydrolaseprovided, LTA-4 Hydrolase, LTA4, LTA4 Hydrolase, LTA4H,)

Antibodies / Antibodies-Enzymes

-20°C

Supplied as a liquid PBS,  0.1% sodium azide,  50% glycerol.

Recombinant full length Human LTA4H.

Leukotrienes are biologically active compounds formed from arachidonic acid or polyunsaturated fatty acids that are important in host defense reactions and play a pathophysiological role in inflammation and allergic reactions. LTA4H (Leukotriene A4-hydrolase ) is a Zn2+-containing enzyme with both epoxide hydrolase and aminopeptidase activity (. As an epoxide hydrolase, LTA4H catalyzes the hydration of LTA4 to leukotriene B4 (LTB4, 5S, 12R-dihydroxy-6, 14-cis-8, 10-trans-eicosatetraenoic acid), a potent lipid chemoattractant that influences inflammation, immune responses, and host defense against infection. As an aminopeptidase, LTA4H catalyzes the cleavage of amides of para-nitroaniline. The human LTA4H gene encodes a 610 amino acid protein.

Applications:
Suitable for use in Western Blot, Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Western Blot: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.