NET1 (ARHGEF8, GLYT2, Guanine Nucleotide Regulatory Protein OncoGene, MGC114559, MGC127767, MGC53602, mNET1, NET1A, Neuroepithelial Cell transforming Gene 1, p65 Net1 proto OncoGene, Rho Guanine Nucleotide Exchange Factor GEF 8) discontinued

Antibodies / Antibodies-Proteins

-20°C

Supplied as a liquid PBS,  0.1% sodium azide,  50% glycerol.

Recombinant full length Human NET1.

Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.

Applications:
Suitable for use in Western Blot, Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Western Blot: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.